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An SOD1 deficiency enhances lipid droplet accumulation in the fasted mouse liver by aborting lipophagy

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Hypothalamic-pituitary-adrenal axis (HPA) disturbance Aberrant activity of the HPA is associated with the clinical course of BD [35]

That these relationships were seen in hepatocytes, myocytes, and brown adipocytes, but were conspicuously absent in fibroblasts, hints that oxidative metabolism might represent an intrinsic challenge to ER functionality and might explain why feeding itself appears to be an ER stressor