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One study has found that, after weight loss on a ketogenic diet, while basal GLP-1 levels significantly increased in both men and women, postprandial GLP-1 levels appeared significantly higher only in the female group and did not significantly differ in the male group (46)

Clinical studies have shown oral semaglutide to have superior efficacy to placebo and to a number of oral and injectable active comparators representative of common drug classes (DPP-4 inhibitors, other GLP-1RAs, SGLT2is), with a safety and tolerability profile consistent with the GLP-1RA class

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The active control was available as an active drug subcutaneously injected on a daily basis in the abdomen, upper arm, or thigh via FlexPen injector

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How much glutathione should I take during GLP-1 therapy? Typical oral glutathione dosing ranges from 250500mg daily for antioxidant support, though clinical evidence for benefit at these doses is limited outside specific disease states