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Semaglutide GLP-1 is a once-weekly injectable medication that can aid in managing chronic weight in adults, especially those with obesity or overweight individuals with at least one weight-related comorbidity like high blood pressure, high cholesterol, or type 2 diabetes

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Key pancreatic markers: Both amylase and lipase can rise modestly on GLP-1 medications without indicating pancreatitis this is a known pharmacological effect

Below, we summarize key findings from preclinical animal studies, followed by human clinical evidence, to delineate how GLP-1microbiota interactions may contribute to the therapeutic actions of this drug class

Secondary endpoints included change from baseline in body weight, total fat mass and DEXA parameters on body composition at week 24

Can be taken at any time of day, with or without food