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It is well-tolerated in animal and early clinical studies, even at multi-milligram doses [12]

Oral preparations of Vitamin B12 may increase serum levels but many patients remain symptomatic until they use sublingual or vitamin B12 injections due to low cellular concentrations 6

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Conflict of interest The authors declare no competing interests

During the daily OsG treatment cycle, plasma glucose was oscillating within the physiological range (between ~100200 mg/dl, Fig

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