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After a 15-year follow-up, T2D patients receiving GLP-1RAs showed significantly reduced relative risk for CRC by 44% compared with insulin (HR, 0.56
The main risk factors include carrying excess weight (particularly around the middle), type 2 diabetes, and high blood pressure
Inhibition of DPP IV by gliadin can result in increased levels of non-metabolized gliadin molecules with opioid activity that can inhibit the typical abdominal pain associated with classical CD (Fig
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