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Toll-like receptor signaling in severe acute respiratory syndrome coronavirus 2-induced innate immune responses and the potential application value of toll-like receptor Immunomodulators in patients with coronavirus disease 2019

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This demonstrates that FOXO4-DRI selectively targets and eliminates senescent Leydig cells by causing p53 nuclear exclusion and subsequent apoptosis

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This process is mediated by ZDHHC17/24 and promotes the phosphorylation and activation of AKT, partly by inhibiting the formation of inactive polymer

Competing Interests The authors declare no competing interests