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PMC 8395423
Novo Nordisk, the Danish pharma company behind several GLP-1RA drugs (including Ozempic/Wegovy and Saxenda) grew its sales by over 30% in 2023, and its share price rose by over 70% in the last year, making it the most valuable European company by market capitalization
The peptide approach is generally considered safer, because the bodys normal feedback loops remain intact its harder to overshoot physiologic levels
If you are a Medicare patient, this program may allow you to access Wegovy or Zepbound for as little as $50 per month
Recently, another selective inhibitor of GLS1, CB-839 (telaglenastat), showed no significant side effects in preclinical trials and is currently undergoing full clinical trials 45
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