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GLP-1RAs can cross the bloodbrain barrier and activate brain GLP-1 receptors, leading to neuroprotection by improving insulin signaling, reducing tau hyperphosphorylation, and enhancing cognitive function in diabetic and aging models
Women with carnitine deficiency appear to secrete insufficient amounts of carnitine into their breastmilk for their breastfed infants, who may require levocarnitine supplementation.[1] Preterm infants are often deficient in levocarnitine and require supplementation.[2] No data exist on the safety and efficacy levocarnitine supplementation in nursing mothers or infants without carnitine deficiency
Rinninella, E
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For example, a DNA repair protein, redox factor Ref-1, was reported to promote the DNA-binding activities of several transcription factors, including HIF-1 and p53, which confers cytoprotective function under hypoxia