This can make it harder for them to absorb and use vitamin B12
Contrave contains naltrexone (an opioid antagonist) and bupropion (an antidepressant)
After the shortages were resolved, many compounders sought to differentiate compounded GLP-1 offerings by adding a second ingredient most frequently vitamin B12/cyanocobalamin to argue the compounded formulation was not the same as the FDA approved product
The American Diabetes Association (ADA) Standards of Care acknowledge these tolerability concerns and recommend gradual dose escalation to minimize gastrointestinal disturbances
Higher levels may indicate active inflammation or developing autoimmune disorders
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