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Drug screening was completed using a 438 Selleck Chemicals library of FDA-approved drugs ( Table S.3)

La meta analisi di 9 studi clinici con 911 partecipanti ha confermato che col tempo nella media i partecipanti sono riusciti a bruciare grassi (1,33 kg contro 0,57 kg), ma svolgendo l'analisi di meta-regressione, la perdita di grasso era quasi zero

These results directly confirm that excessive NNMT activation suppresses NAD+ synthesis and impairs energy metabolism, while NNMT inhibition effectively reverses this process, establishing NNMT as a negative regulator of energy metabolism

However, this varies from individual to individual

2021. NNMT inhibition reduces obesity and diabetes risk

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