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Evidence-based management of endometriosis involves a multimodal approach tailored to symptom severity, fertility goals, and patient preferences

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The large and growing share of people of all ages are obese

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Pharmas relentless push to go from 2x/day (730/year) to 1x/week (52/year) and eventually to monthly and yearly can dramatically reduce the overall burden of managing a chronic disease for patients, significantly increasing persistence and therefore efficacy of the treatment and ultimately, healthspan and lifespan

However, persistent or severe headaches warrant medical evaluation to exclude other causes and ensure appropriate management