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Schematic showing how the iron-sulfur clusters-containing protein LIAS enables OGDH and PDH activity by transferring lipoic acid as a cofactor to their enzyme complexes (top left)

Normal infant weight gain and feeding patterns are critical indicators of health during the first year of life, and any interference with these processes could have developmental consequences

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This is a shift from earlier estimates (including on this page) that pointed to a Q4 2026 NDA filing based on TRIUMPH-1 and TRIUMPH-4 data alone

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The body has already adapted to substantial receptor activation