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This focus led to significant breakthroughs, but it became clear in animal models that single-pathway stimulation had a ceiling effect regarding metabolic stabilization and lipid management
Acute, subacute and chronic toxicities affect many organs and systems in the body (Fig
These options are not available to everyone and come with their own trade-offs, but they deserve consideration when injection site reactions significantly impact quality of life
The first objective landmark I rely on is the peak reticulocyte count 1 week after starting treatment
Nausea and Vomiting Up to 50% of patients experience nausea, especially in the first few weeks
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