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Price et al

Both affect skin, but through different mechanisms

GHK-Cu also encourages the production of other key components of the skin matrix, including elastin, proteoglycans, and glycosaminoglycans like hyaluronic acid

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The first is extracellular matrix biology: fibroblast culture and rat wound-chamber work from the Maquart and Simeon groups reported that GHK-Cu stimulates collagen, glycosaminoglycan and small proteoglycan synthesis while simultaneously upregulating matrix metalloproteinase-2 and its tissue inhibitors, a combined synthesis-and-turnover signature unusual among matrix-active compounds

This allows your skin to gradually build tolerance and receive the full benefits of each ingredient