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J Biol Chem 269:85358540 Mller M, Carell T (2009) Structural biology of DNA photolyases and cryptochromes

Furthermore, the GSH-dependent antioxidant enzymes (glutathione peroxidase-1, glutathione reductase, glutathione S-transferase) cooperate and are interconnected reactions that eliminate ROS or controlled the redox state

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Swapping in the triple agonist is the upgrade path, with the trade-off being that the specific pairing has not been formally trialed

Its significance is rooted in its endogenous nature

The trade-off is that the 1mg starting dose becomes just 10 units, which can be difficult to measure precisely on a standard syringe