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People who notice they drink less on a weight medication are a real signal, but they were not randomly assigned, and many other things about their lives changed at the same time
"Phase I Randomized Placebo-controlled, Double-blind Study of the Safety and Tolerability of Bremelanotide Coadministered With Ethanol in Healthy Male and Female Participants." Clinical Therapeutics
At 2.5 mg/ml concentration, 250 g = 0.1 ml = 10 IU on an insulin syringe
Clinical check-ins and symptom logs allowed clinicians to slow escalation rather than stop therapy, preserving continuity and reducing avoidable discontinuations
Due to the demand for this drug for weight loss, most insurance companies are requiring patients to prove that they have been diagnosed with type 2 diabetes before they will pay for this drug
Novo Nordisk then used the Semaglutide formula to create an FDA-approved weight loss drug called Wegovy
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