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doi: 10.3389/fphar.2022.983233 Received 30 June 2022 Accepted 29 July 2022 Published 22 August 2022 Volume 0 - 2022 Edited by Simona Pichini, National Institute of Health (ISS), Italy Reviewed by Stphen Manon, CNRS, UMR5095, France Antonio Leo, Scuola di Medicina e Chirurgia, Universit Magna Grecia di Catanzaro, Italy Updates Copyright 2022 Ghosh, Westcott, Perucca, Hossain, Bingaman and Najm