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FranceschiCCapriMMontiDGiuntaSOlivieriFSeviniFet alInflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans

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Research published in 2011 found that elderly subjects had markedly lower glutathione concentrations compared to younger adults, with 83% higher fractional synthesis rates in young people

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Diet F, Pratt RE, Berry GJ, Momose N, Gibbons GH, Dzau VJ

In addition, it is notable that phase I studies of BSO administered with the anticancer drug melphalan demonstrated that continuous infusion of BSO was relatively non-toxic and resulted in depletion of tumor GSH (16,17)