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This warning applies if someone has a personal or family history of medullary thyroid carcinoma or MEN-2

However, Ozempic is sometimes used off-label as a weight loss drug

P.ReisP.et al

The most commonly reported adverse effects in these trials were gastrointestinal in nature including nausea, vomiting, diarrhoea, and constipation consistent with the broader class of GLP-1 receptor agonists

However, select food intake data points were excluded from analysis because of food shredding behaviour (noted at the time of measurement), so we were unable to obtain accurate measurements in food intake for all mice

Without the metabolic support of tirzepatide, caloric intake tends to increase while the bodys reduced metabolic rate (from weight loss) makes it easier to regain weight than to maintain it