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Moreover, while OCCC show intrinsic resistance to conventional platinum-based chemotherapy, OSC exhibit at first sensitiveness to platinum-based chemotherapy, though the majority of cases develop chemoresistance during the course of treatments 33,34

If sleep problems persist despite optimizing all the factors within your control, consultation with a sleep medicine specialist may be warranted

Hearing loss from cisplatin is often irreversible and more pronounced in pediatric patients (Meijer et al

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Bcl-2 is a novel interacting partner for the 2-oxoglutarate carrier and a key regulator of mitochondrial glutathione