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Safety is one of the most common concerns

Common pitfalls with cell viability assays are: Assays lack sensitivity threshold required for reproducibility and high-throughput screening Lacking an option for kinetic monitoring Viability assays measure how many cells are alive, but not whether theyre actively dividing

doi: 10.1016/j.mib.2024.102507 23 ChuH.DuanY.LangS.JiangL.WangY.LlorenteC.et al

However, this concern is not supported by larger and more systematic analyses of short-term data from clinical trials and observational studies

Thus, activation of Nrf2 appears to be an attractive approach for treating or mitigating PD 9

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