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Sexton DJ et al

No tolerance development appears to occur, unlike many pharmaceutical compounds

mRNA stability and selenocysteine insertion sequence efficiency rank gastrointestinal glutathione peroxidase high in the hierarchy of selenoproteins

Thus, PG levels, which are known to protect the gastric mucosa by increasing blood flow, were not altered by NPW treatment, while blockade of COX enzymes reduced the PG levels

Treatment outcomes vary from person to person, and no guarantee of results is intended or implied