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Semaglutide is a GLP-1 receptor agonist that works by: Suppressing Appetite: The medication reduces hunger signals in the brain, helping individuals consume fewer calories

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By using genetic proxies for these therapeutic targets, we aim to clarify their potential roles in treating MASLD and its complications, providing crucial evidence to guide future clinical drug development

GLP-1 also improved all assessed weight-related and cardiometabolic indicators

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Not only does it trigger insulin release from the pancreas, but it can also block glucagon production