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[ref] A 2025 study showed that patients with RLS had higher serum IL-13 (inflammatory cytokine) levels and altered natural killer cell levels.[ref] The IL-13 connection is interesting, since IL-13 is elevated in asthma and allergies, tying back to altered histamine levels in the brain

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Why Medical Oversight Matters GLP-1 treatment needs a supervisors check and follow-up care

Hormonal changes beyond insulin also affect mood

For multi-arm studies or extended longitudinal work where between-condition consistency is a controlled variable, drawing from a single sealed 40mg supply is the cleaner experimental design

Block G, et al