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10.1016/j.freeradbiomed.2020.02.027 68 Usategui-MartnR.Puertas-NeyraK.Galindo-CabelloN.Hernndez-RodrguezL

This bivalent effect of aminothiols (pro-oxidant and antioxidant), confirmed for in vitro LDL oxidation (Halvorsen et al, 1996), might explain the discrepancies observed between moderate and severe hyperhomocysteinemia

Efficacy remains unproven in healthy populations

10.1111/j.1365-2265.2006.02627.x

Desventaja : menor potencia individual vs GHRP-2/Hexarelina (compensada con combinacin con GHRH anlogo)

It can be clinically relevant to appreciate that these secondary effects of vitamin B 12 deficiency could be central to its pathophysiology