A BMI of 27 or greater (classified as overweight) in the presence of at least one weight-related medical condition, such as hypertension (high blood pressure), Type 2 diabetes, or high cholesterol
Tirzepatide ODT is a solid tablet that dissolves on the tongue, while tirzepatide drops are a liquid formulation placed under the tongue
Mild to moderate diarrhea is common during the adjustment phase and rarely dangerous on its own
On the other hand, GLP-1 RA can reduce epicardial fat and semaglutide 2.4 mg have shown to improve physical function and symptoms in people with HFpEF [93]
Serious But Rare Risks All classes carry potential serious risks requiring monitoring
"Pharmacology, physiology, and mechanisms of incretin hormone action." Cell Metabolism , 17(6), 819-837