Depending on the nature of the substance and especially the attacked group, several reactions can take place: glucuronidation conjugation of a COOH or OH group with glucuronic acid, acetylation isoniazid, sulfonamides, aniline derivatives, polymorphism in acetylase makes treatment of tuberculosis with isoniazid problematic conjugation with glycine acetylsalicylic acid, nicotinic acid, conjugation with glutathioneem epoxides, nitro compounds, ethacrynic acid, formation of ethereal sulfates minor pathway of phenolic compounds
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The combination of these 4 peptides aims to achieve a synergistic effect greater than the sum of each individual component
Rewiring neuronal glycerolipid metabolism determines the extent of axon regeneration
RIF was administered at 16 mg/kg daily via oral gavage for the first 3 days
there were no adverse events [50]