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In epithelial cells macropinocytosis is strongly connected to oncogenic activation and actin cytoskeleton rearrangements which are generally involved in cancer progression, and for this reason inhibition of macropinocytosis as means to prevent cholesterol uptake could be a useful approach in cancers that can activate it

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5.2.5.1 Review of Traditional Pharmacopoeia To identify plants with potential positive performance-enhancing effects, a thorough review of ethnomedicine literature and pharmacological studies was conducted at global level

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