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Preclinical and clinical evidence includes several noteworthy findings

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It occurred in 13.4% of the lixisenatide group vs 13.2% of the placebo group: hazard ratio=1.02

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Choline, inositol, and methionine are studied for their roles in hepatic phosphatidylcholine production (required for VLDL export of fat from the liver), methylation cycle function, and one-carbon metabolism pathways central to NAFLD and metabolic syndrome research