When muscle mass drops too much: Your metabolism slows down , so you burn fewer calories You lose strength, stability, and energy You may regain fat more easily after stopping the medication You increase your risk of long-term frailty and poor body composition The goal isnt just to lose weight its to lose fat while keeping (or gaining) strength
,
This is why the strict fasting requirement exists: taking Rybelsus on an empty stomach, with only a small amount of plain water (up to 120ml), and waiting at least 30 minutes before consuming anything else maximises the amount of active drug that enters the bloodstream
Research published in Nature Reviews Endocrinology and other medical journals indicates that early studies suggest GLP-1 medications may reduce cravings for substances such as alcohol, nicotine, and highly processed foods
Chronic Stress and Cortisol Elevated cortisol the primary stress hormone directly promotes fat storage in the abdominal region, increases appetite for high-calorie foods, and impairs insulin sensitivity
L-Carnitine also increases insulin sensitivity, especially in muscle tissue, which may support fat loss and muscle recovery by improving nutrient uptake