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Bone health: calcium and vitamin D Rapid weight loss is one of the recognised risk factors for bone loss, and the Wegovy product information lists hip fracture as a rare adverse reaction in SELECT

Diabetes drugs and weight loss

second-generation long-acting analogues such as cagrilintide under late-stage clinical development, often combined with GLP-1 therapy for enhanced weight loss), (b) small molecules or peptides designed to inhibit amylin misfolding and aggregation to protect -cells, and (c) immunotherapeutic or vaccine approaches targeting pathological IAPP species

Semaglutide 24 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial

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For example, use of a GLP-1 cut a patient's odds of kidney failure by 16% and a worsening of their kidney function by 22%, Budve and team reported