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However, the majority of adverse events in both treatment groups were mild-to-moderate GI events, with the most common being transient nausea [39]
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Based on published phase 2 clinical trial data, the most commonly reported adverse effects include: Gastrointestinal effects: Nausea, vomiting, diarrhoea, constipation, and reduced appetite are the most frequently reported side effects
Patients with severe kidney disease, a history of severe gastrointestinal disease, or significant liver impairment should discuss the risks carefully with their prescriber before starting any tirzepatide product
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