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If suspected, reduce dose by 25-50% and monitor response
Semaglutide is an alternative to other weight loss medications, like Qsymia, Contrave and Xenical which can have severe side-effects if you are taking medications for hypertension or other heart issues
doi:10.1038/s41401-024-01250-7
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Initially, incretin therapies focused on synthesizing GLP-1 analogues that were resistant to degradation by dipeptidyl peptidase-4 (DPP-4), which rapidly breaks down endogenous GLP-1 (Rhrborn et al., 2015)
