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Antidrug antibodies in psoriasis: a systematic review
53 Depending on the original ligand, the outcomes of the binding to the ERE are agonistic (stimulatory) of or antagonistic (inhibitory) on gene action, compared to that of estradiol binding
The underlying mechanism appears to involve modulation of oxidative stress and inflammatory pathways, particularly by inhibiting NF-kB signaling (James et al., 2023)
doi: 10.1371/journal.pone.0172604 122 GrabenhorstFRollsETParrisBAdSouzaAA
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