Eli Lilly and Company;2018
Semaglutide has the longest safety record, with data now extending beyond five years in the cardiovascular outcomes trials
The concentration listed on the label reflects pharmaceutical-grade preparation, with each batch tested for potency, sterility, and endotoxin levels
A survey of US adults suggested that, although 45% of adults were interested in GLP-1 receptor agonist use for weight management, this proportion declined to 14% after sharing that weight regain was likely after discontinuation (Montero et al, 2023)
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The changes may occur within months rather than years, creating the impression of premature ageing even as health improves