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2009, 4: e4512- 10.1371/journal.pone.0004512 Lo R, Turner MS, Barry DG, Sreekumar R, Walsh TP, Giffard PM: Cystathionine -lyase is a component of cystine-mediated oxidative defense in Lactobacillus reuteri BR11

To remove H 2 O 2 excess, GPx, TrxR, and CAT (i.e., enzymes involved in EAS) are dependent on reduced nicotinamide adenine dinucleotide phosphate (NAPDH) for the renewal of its substrate, thereby enabling the clearance of ROS