SURPASS-CVOT (N=13,165) noninferior on 3-point MACE (HR 0.92), with 4-point MACE HR 0.88 and all-cause death HR 0.84: Heerspink SURPASS-4 kidney post-hoc
Table 2 Published clinical trials with oHSV
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It acts on G-protein coupled receptors mostly expressed in pancreatic -cells, but is also found in adipose tissue, stomach, and bone [19]
Variability in Response Some people experience rapid appetite suppression and early weight loss, while others see more gradual changes