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Patients were randomized in a 1:1:1 ratio to once weekly fixed dosage of ZEPBOUND 10 mg, ZEPBOUND 15 mg, or placebo with an escalation period of up to 20 weeks followed by the maintenance period

We usually start with a low dose and slowly increase it to help your body adjust

Large, wellcontrolled randomised trials are needed to characterise benefits and risks, with designs that distinguish weightlossmediated effects from direct pharmacology

Published meta-analyses show berberine reduces fasting blood glucose by roughly 1015 mg/dL and HbA1c by 0.50.6% in people with type 2 diabetes or metabolic syndrome (Liang et al., 2019

Ipamorelin, a new growth hormone releasing peptide with selectivity for the growth hormone secretagogue receptor