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PMC 3711460
ChemBioChem 22 , 949960 (2021)
With regard to catalytic mechanism, all the seleno-GPxs share the common pathway which starts with the binding of hydroperoxides and GSH at the catalytic and thiol binding motifs, respectively [8, 11,12,13,14,15,16,17,18]
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It contributes to avoid catabolism or loss of muscle mass
So why is there a discrepancy between these findings and those of meta-analyses of published Mendelian randomization studies
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