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Moreover, GHK-Cu significantly inhibited the LPS-induced phosphorylation of p38 MAPK and slightly decreased the phosphorylation of JNK1/2, while having no observable effect on ERK1/2
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beyond that trial and the halted Phase 2 lipodystrophy study, there are no completed human trials measuring body composition, strength, or long-term safety outcomes, so evidence for bodybuilding-related benefit claims remains preliminary and largely extrapolated from the hormone's known biology rather than from direct testing of CJC-1295
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There may be implications for liver, kidney, or thyroid function in some individuals
