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Bianchini G, Nigro C, Sirico A, Novelli R, Prevenzano I, Miele C, et al
These are typically administered via subcutaneous injection at standard therapeutic doses as recommended in the manufacturer's Summary of Product Characteristics (SmPC) and regulatory bodies such as the MHRA
This includes considering GLP-1 receptor agonists like Rybelsus for people with type 2 diabetes who have a body mass index (BMI) of 35 kg/m or higher (or 32.5 kg/m or higher for those of South Asian or Chinese descent) and who would benefit from weight loss, or when insulin therapy would have significant occupational implications or weight gain would cause significant clinical or psychological problems
Studies suggest DSIP may act through multiple mechanisms including GABA receptor interaction and hypothalamic-pituitary axis regulation
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