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When the body carries excess weight for months or years, this framework stretches to accommodate the increased volume

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For instance, a study in 2024 showed that when the concentration of bilirubin in serum reaches a certain value, the antioxidant effect of bilirubin begins to reduce, and even induces oxidative stress and thus promotes the development of cancer (183)

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Inflammation burden and routine stability Chronic low-grade inflammation is associated with reduced training tolerance and difficulty sustaining routines