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PubMed , Current Pharmaceutical Design , vol

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(2016) demonstrated that blocking estrogen receptor signaling abolished the suppressive effects of GLP-1R activation on reward-related behavior, further supporting the idea that estrogen is a critical modulator of GLP-1s central effects on motivated responding

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Each dose is administered as a subcutaneous injection, typically in the abdomen, thigh, or upper arm [2]

PMC 4894846