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Acrolein can cause cardiovascular disease: a review
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This makes bedtime dosing optimal, as it amplifies the natural nocturnal GH surge without disrupting the diurnal secretory rhythm
However, the therapeutic utility of doxorubicin is undermined by its dose-dependent cardiotoxicity, possibly arising as a result of futile redox cycling, with NADH dehydrogenase within the mitochondria proposed as the most likely site of anthracycline reduction 9,10
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Freezer storage at minus 20 degrees Celsius maintains potency for 2 to 3 years
