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Description

Key interactions by conserved polar amino acids located at the transmembrane helical boundaries in Class B GPCRs modulate activation, effector specificity and biased signalling in the glucagon-like peptide-1 receptor

doi: 10.1093/JAS/SKAE202 119 TadichL

The nausea associated with semaglutide is thought to result from both peripheral effects on gastric emptying and central effects on nausea centers in the brain