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Accordingly, a downstream partner of the PERK pathway, the C/EBP-homologous protein (CHOP), is activated upon 6-hydroxydopamine (6-OHDA) administration (Holtz and OMalley, 2003), while ablation of CHOP is protective against 6-OHDA toxicity (Silva et al., 2005)

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Production of large amounts of hydrogen peroxide by human tumor cells

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doi: 10.1038/s41420-024-02078-0 94 YinXZhuGWangQFuYDWangJXuB

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