Roughly 80% or more of participants on tirzepatide lost more than 5% of their body weight
One of the most common issues is gastrointestinal discomfort, which can include nausea, vomiting, diarrhea, constipation, and abdominal pain
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Harder stools Increased bloating More abdominal discomfort Feeling overly full after eating Less frequent bowel motions Some people do perfectly well on GLP-1s with the right support, but others find constipation becomes significantly worse especially if hydration, food intake or fibre balance arent carefully managed
2123 The Effect of GLP-1RAs on Systemic Inflammation The ability of GLP-1RAs to reduce systemic inflammation (with decreases in hs-C-reactive protein, TNF-, interleukin-6 and interleukin IL-1) has been demonstrated in animal studies, studies on isolated human tissues and RCTs
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