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A Phase I clinical study conducted by Dorr et al

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In particular, to recapitulate the proliferative phase, organoids are exposed to an estrogen receptor (ER) agonist (typically E2), while a combination of E2 with a progesterone receptor (PGR) agonist (typically P4 or medroxyprogesterone acetate (MPA)) and decidualization-promoting cyclic adenosine monophosphate (cAMP) is employed to replicate the transition to the secretory phase [53, 54, 63]

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El equilibrio de GLP-1 se refiere al balance dinmico entre la produccin, liberacin, accin y degradacin del pptido similar al glucagn tipo 1, una hormona intestinal fundamental para la regulacin metablica

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