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Research Questions But more research is needed to paint a definitive picture of the effect of the drugs on womens health
These medications work through multiple complementary mechanisms
No matter the dose, people on orforglipron lost more weight and saw a greater reduction in blood sugar than people on placebo, the study found
It also caused both visceral fat and subcutaneous fat to be less sensitive to insulin
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Primary outcomes were total body weight loss percentage after 12 months of semaglutide treatment based on hormone therapy use status, the percentage of women who achieved 5% or greater and 10% or greater total body weight loss, and changes in glucose, blood pressure and lipids at 12 months
