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In a combination protocol, some researchers theorize that starting at a lower dose (1mg daily) and assessing tolerance before escalating to the full 2mg might reduce the risk of compounding side effects with retatrutide

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cardiovascular disease

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Effects of GLP-1-(7-36)NH2, GLP-1-(7-37), and GLP-1- (9-36)NH2 on intravenous glucose tolerance and glucose-induced insulin secretion in healthy humans

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For example GLP-1s are being studied for treatment of other illnesses, like cardiovascular disease, heart failure, liver disorders, and obstructive sleep apnea

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Falutz, J., et al

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